许莹,姜雯娟,王琲,李延超,曲晨,等.丹参多酚酸盐对老年缺血性脑卒中患者超敏C反应蛋白及运动认知功能影响的研究[J].,2018,5(9):16-19.
丹参多酚酸盐对老年缺血性脑卒中患者超敏C反应蛋白及运动认知功能影响的研究
Effects of Salvianolate on Hypersensitive C-reactive Protein and Cognitive Function in Aging Stroke Patients
投稿时间:2018-06-21  最后修改时间:2018-07-11
DOI:10.12095/j.issn.2095-6894.2018.09.004
中文关键词:  脑卒中,注射用丹参多酚酸盐,超敏C反应蛋白,运动障碍,认知障碍
英文关键词:Stroke; Salvianolate; hypersensitive C-reactive protein; Movement disorders; Cognition disorders
基金项目:新疆维吾尔自治区卫生计生委青年科技人才专项科研项目,2016Y23;江苏省青年医学人才项目,QNRC2016666
作者单位E-mail
许莹 南京鼓楼医院,江苏南京210000  
姜雯娟 新疆维吾尔自治区人民医院,新疆乌鲁木齐830000  
王琲 新疆维吾尔自治区人民医院,新疆乌鲁木齐830000  
李延超 新疆维吾尔自治区克州人民医院,新疆阿图什845350  
曲晨 南京医科大学第二附属医院 logairland@163.com 
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中文摘要:
      【摘 要】目的:研究注射用丹参多酚酸盐对老年脑卒中患者超敏C 反应蛋白(hs?CRP)及认知功能的影响。方法:选取2016 年   1 月至2017 年12 月在南京医科大学第二附属医院老年医学科住院的老年脑卒中患者共52 人为研究对象,其中使用常规治疗的   患者20 例为对照组,在常规治疗的基础上加用注射用丹参多酚酸盐32 例为研究组。检测hs?CRP 并使用美国国立卫生院神经   功能缺损程度评分(NIHSS)和改良RANKIN 量表(mRS)进行运动功能评分,使用蒙特利尔认知评估量表(MoCA)进行认知功能   评估。结果:治疗前两组患者的hs?CRP、NIHSS 评分、mRS 评分及MoCA 评分比较,差异无统计学意义(P>0.05)。两组患者治疗   后的hs?CRP及NIHSS 评分显著低于治疗前,MoCA 评分显著高于治疗前,差异具有统计学意义(P<0.05)。治疗后研究组患者的   hs?CRP显著低于对照组,MoCA 评分显著高于对照组,差异具有统计学意义(P<0.05)。结论:注射用丹参多酚酸盐可以改善老年   脑卒中患者超敏C 反应蛋白及老年脑卒中患者的认知功能
英文摘要:
      【Abstract】Objective: To effect of Salvianolate on high?sensitivity C?reactive protein (hs?CRP) and cognitive function in elderly stroke   patients. Methods:A total of 52 elderly stroke patients were enrolled in the Department of Geriatrics of the Second Affiliated Hospital of   Nanjing Medical University from January 2016 to December 2017. Among them, 20 patients received routine treatment were selected as   control group, and 32 cases received additional salvianolate were selected as the study group. hs?CRP was measured and motor function   were scored using the NIHSS and mRS, and cognitive assessment was performed using the MoCA. Results: There was no significant differ?   ence in hs?CRP, NIHSS, mRS and MoCA between the two groups before treatment (P>0.05). In both groups, the hs?CRP and NIHSS   after treatment were significantly lower than those before treatment, and the MoCA was significantly higher than that before treatment(P<   0.05). The hs?CRP of the study group was significantly lower than that of the control group, and the MoCA was significantly higher than
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